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Cell Biology of Metals (GRS)

Gordon Research Seminar

Mechanisms of Metal Acquisition, Storage, Trafficking and Homeostasis

October 16 - 17, 2021

Chair Liu Liu

Mount Snow

89 Grand Summit Way

West Dover, VT, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Cell Biology of Metals is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of the 2021 GRS will be on the mechanisms by which metals are sensed and acquired from the environment, stored within cells, and trafficked to maintain homeostasis. Additionally, the 2021 GRS welcomes researchers who study metals and metal complexes in a cellular environment with novel approaches e.g. computational tools, high throughput sequencing, bioinformatics, and high-resolution microscopy. This year’s GRS will feature several sessions with short talks selected from submitted abstracts, poster sessions, and a small group mentoring session.

Related Meeting

This GRS will be held in conjunction with the "Cell Biology of Metals" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Strategies for Cellular Metallocofactor Trafficking Discussion Leader: Debolina Hati (University of South Carolina, USA)
3:45 pm - 4:15 pm	Ruma Banerjee (University of Michigan, USA) "Trafficking B₁₂"
4:15 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Sensing, Acquisition and Homeostasis of Critical Metals for Life Discussion Leader: Harsha Gouda (University of Michigan, USA)
7:30 pm - 7:45 pm	Radhika Mehta (University of California, Berkeley, USA) "Fluorescent Probes to Explore Metalation and Evolution Characteristics of Zinc Metalloproteins"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	Jiansong Xu (Pennsylvania State University, USA) "The NiCo Riboswitch as an Iron-Responsive Riboswitch: A New Mechanism of Bacterial Iron Regulation"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	Jennifer Gamarra (Columbia University, USA) "The Manganese Transporter SLC30A10 Is Regulated by Bile Acid Composition in Intestine"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	Anindita Sarkar (University of Michigan, USA) "Elucidating the Heme Chapter of Rev-Erbß"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	Evan Talib (University of South Carolina, USA) "Characterization of the Interaction Between GRx4-Bol2 and the Iron-Responsive Transcription Factor Aft1 in Candida glabrata"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	Adelita Mendoza (Washington University, USA) "Lysosomes Mediate Zinc Trafficking via Morphological Restructuring and Zinc Transporters"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Metals in Health, Physiology and Diseases Discussion Leader: Caitlin Murdoch (Vanderbilt University Medical Center, USA)
9:00 am - 9:15 am	Tyree Wilson (University of Maryland, Baltimore, USA) "The Heme Binding Protein PhuS Regulates the Pseudomonas aeruginosa Tandem sRNA PrrF1, F2 Locus"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	Chuchu Guo (Massachusetts Institute of Technology, USA) "A Heavy-Metal Trojan Horse: Enterobactin-Based Delivery of Platinum(IV) Prodrugs to Gram-Negative Bacterial Pathogens"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	Helen Liu (University of California, Berkeley, USA) "The Chlamydomonas Fe-Ome"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	Matthew Jordan (Indiana University, USA) "The Impact of Zn Limitation on Translation in Acinetobacter baumannii"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	Milan Prajapati (Brown University, USA) "Liver Mn Excess Causes Erythropoietin Excess and Polycythemia in a Mouse Model of Inherited Manganese Excess"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	Natalie Garza (Texas A&M University, USA) "A Genome-Wide Copper-Sensitized Screen Identifies Novel Regulators of Mitochondrial Cytochrome C Oxidase Activity"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Development Panel Discussion Discussion Leaders: Anindita Sarkar (University of Michigan, USA) and Jonathan Barra (Albany Medical College, USA)
1:30 pm - 2:30 pm	Panel Discussion Effective Professional Networking: Skills and Platforms Mishtu Dey (Cell Chemical Biology, Cell Press, USA) Angela Wilks (University of Maryland, USA) Angela Fleischhacker (University of Michigan, USA) Vivek Sharma (MassBiologics, UMass Chan Medical School, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Conference ID: 17439

Contributors

Funding for this conference was made possible (in part) by 1R13DK130226-01 from NIDDK. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.